Canale V C, Volpe R, Carbone A, Grigoletto E
J Laryngol Otol. 1983 Jun;97(6):553-6. doi: 10.1017/s0022215100094561.
A case report of a Stage III botryoid rhabdomyosarcoma of the nasopharynx associated with a six-and-a-half-year survival is presented. Treatment consisted of surgery, radiotherapy (6,000 rads TCT) to the nasopharynx and maxillary sinuses bilaterally, and six cycles of polychemotherapy with Vincristine, Adriamycin, Cyclophosphamide and DTIC, without major loss of function or cosmetic deformity. The histology of the lesion is discussed with reference to recent classification and prognosis. The authors suggest that the histological type and prognosis of rhabdomyosarcoma of the nasopharynx in children may be better correlated in future studies.
本文报告一例鼻咽部III期葡萄状横纹肌肉瘤患者,其存活期长达六年半。治疗方法包括手术、双侧鼻咽部和上颌窦放疗(总量6000拉德),以及六个周期的多药联合化疗,使用长春新碱、阿霉素、环磷酰胺和达卡巴嗪,治疗后未出现功能严重丧失或美容缺陷。结合近期的分类和预后情况对病变的组织学进行了讨论。作者认为,在未来的研究中,儿童鼻咽部横纹肌肉瘤的组织学类型与预后可能具有更好的相关性。