Shimosaka S, Waga S
J Neurosurg. 1983 Jul;59(1):158-61. doi: 10.3171/jns.1983.59.1.0158.
Cerebral chromoblastomycosis is a rare intracranial lesion. This lesion was found in a 23-year-old man, who presented with right proptosis and fainting attacks. Computerized tomography revealed a moderately enhanced irregular mass in the right frontal region. Angiography disclosed that the mass was avascular. At surgery, a hard elastic avascular tumor was totally removed piecemeal. Histological diagnosis was a granuloma of fungal origin. Characteristic brown pigments in the hyphae of fungus in the granuloma strongly suggested that the fungus was chromoblastomycosis. The postoperative course was complicated by meningitis and rupture of fungal aneurysms. The patient remained vegetative and died 2 1/2 years later. The literature on such fungal aneurysms is briefly reviewed; no previous case of fungal aneurysms associated with cerebral chromoblastomycosis could be found.
脑着色芽生菌病是一种罕见的颅内病变。该病变见于一名23岁男性，表现为右眼球突出和昏厥发作。计算机断层扫描显示右额叶有一个中等强化的不规则肿块。血管造影显示该肿块无血管。手术中，一个硬的弹性无血管肿瘤被逐块完整切除。组织学诊断为真菌性肉芽肿。肉芽肿中真菌菌丝内特征性的棕色色素强烈提示该真菌为着色芽生菌。术后病程并发脑膜炎和真菌性动脉瘤破裂。患者呈植物人状态，2年半后死亡。本文简要回顾了有关此类真菌性动脉瘤的文献；未发现此前有与脑着色芽生菌病相关的真菌性动脉瘤病例。
