Ing M R
J Pediatr Ophthalmol Strabismus. 1983 Jan-Feb;20(1):11-8. doi: 10.3928/0191-3913-19830101-02.
To provide sufficient numbers of patients varying in age of initial adequate surgical alignment for congenital esotropia, 154 patients managed by seven ophthalmologists in three countries were personally examined by the author and the results compiled for a clinical study. Examiner bias was minimized by having the examination performed without prior knowledge of the clinical history and the tests were standardized in both method of examination and test devices. From this population group 106 patients were chosen who had reliable answers, satisfactory alignment and an ophthalmologist's exam of the congenital nature of the problem by at least one year of age. The results of sensory testing showed that those adequately aligned by the age of 6 months versus 12 months versus 24 months were not statistically different, but those patients aligned after 24 months of age demonstrated a significantly lower percentage with evidence for binocularity (p less than .001).
为了获得足够数量的先天性内斜视患者，这些患者在初次获得充分手术矫正时年龄各异，作者亲自检查了三个国家的七位眼科医生所诊治的154例患者，并汇总结果用于一项临床研究。通过在不了解临床病史的情况下进行检查，将检查者偏差降至最低，并且检查方法和测试设备均实现了标准化。从该人群中选出106例患者，他们给出了可靠的答案，眼位矫正良好，并且至少在一岁时经过眼科医生检查确定问题为先天性。感觉测试结果表明，6个月龄、12个月龄和24个月龄时获得充分眼位矫正的患者之间无统计学差异，但24个月龄后获得眼位矫正的患者中，双眼视证据的比例显著更低（p<0.001）。
