Cooke T D
J Rheumatol. 1983 Apr;10(2):288-90.
A review of 62 operated cases with osteoarthritis (OA) indicated clinical evidence of polyarthritis in over 80%. In most cases features of generalized osteoarthritis (GOA) were found. Hand joint arthritis was prominent but, along with the other affected joints, usually asymptomatic. The coexistence of knee disease in cases with hip arthritis and the low incidence of hip changes in those with knee involvement suggest differences in cause for hip disease. These data indicate that the concept of OA as an oligoarticular lesion induced by mechanical or aging processes is inappropriate in a major proportion of knee and hip cases that present for joint replacement. They support the notion that an intrinsic tissue defect is involved in the etiopathogenesis of GOA.
对62例骨关节炎（OA）手术病例的回顾表明，超过80%有临床证据显示多关节炎。大多数病例发现有全身性骨关节炎（GOA）的特征。手部关节关节炎很突出，但与其他受累关节一样，通常无症状。髋关节炎病例中膝关节疾病的并存以及膝关节受累病例中髋关节变化的低发生率表明髋关节疾病的病因存在差异。这些数据表明，在因关节置换而就诊的大多数膝关节和髋关节病例中，将OA视为由机械或衰老过程引起的少关节病变的概念是不合适的。它们支持这样一种观点，即内在组织缺陷参与了GOA的发病机制。
