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[脑病的母体和围产期前驱因素:它们对不明原因脑病试验性分类的作用]

[Maternal and perinatal antecedents of encephalopathies: their contribution to a trial classification of encephalopathies of unknown origin].

作者信息

Laumon B, Mamelle N, Routhier J L, Mamelle J C

出版信息

Pediatrie. 1983 Jan-Feb;38(1):7-21.

PMID:6866644
Abstract

We had a sample of 135 mentally retarded children, whose case history (maternal, obstetrical and perinatal) was known before their mental retardation was suspected. This analysis made it possible to pinpoint characteristic anamnesic giving rise to mental retardation by comparison with a check population. It appears that these factors differ according to the supposed origin of mental retardation (genetic, embryonic, foetal, perinatal and postnatal periods) therefore, they can be considered "explicative" of these origins. A multivariate analysis of these factors indicates that the majority of cases of mental retardation with unknown origin are due to disorders during foetal life, which had not been detected.

摘要

我们有135名智障儿童的样本,在他们被怀疑患有智力迟钝之前,其病史(母亲、产科和围产期)就已为人所知。通过与对照人群比较,这种分析能够找出导致智力迟钝的特征性记忆情况。似乎这些因素根据智力迟钝的假定起源(遗传、胚胎、胎儿、围产期和出生后时期)而有所不同,因此,它们可被视为这些起源的“解释性因素”。对这些因素的多变量分析表明,大多数病因不明的智力迟钝病例是由于胎儿期未被检测出的疾病所致。

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