Adams P C, Robinson A, Reid M M, Vishu M C, Livingston M
Postgrad Med J. 1983 Jan;59(687):31-3. doi: 10.1136/pgmj.59.687.31.
Four cases are described in which the drug mianserin was implicated in the development of leucopenia. In one case this was accompanied by fatal aplastic anaemia. In a second, generalized bone marrow depression occurred, although leucopenia was the only clinically significant manifestation. Mianserin may depress bone marrow function and haematological surveillance is appropriate for patients taking this drug.
本文描述了4例与米安色林药物相关的白细胞减少症病例。其中1例伴有致命的再生障碍性贫血。第2例出现了全身性骨髓抑制,尽管白细胞减少是唯一具有临床意义的表现。米安色林可能会抑制骨髓功能,因此对服用该药物的患者进行血液学监测是合适的。