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日本鹌鹑输卵管体外的肾上腺素能和胆碱能活性

Adrenergic and cholinergic activity of the Japanese quail oviduct in vitro.

作者信息

Arjamaa O, Talo A

出版信息

Poult Sci. 1983 Apr;62(4):665-9. doi: 10.3382/ps.0620665.

DOI:10.3382/ps.0620665
PMID:6866902
Abstract

The responses to isoprenaline, phenylephrine, and carbachol in different segments of isolated intact oviduct were studied. Smooth muscle electrical activity was recorded with suction electrodes placed, one electrode in each, in the infundibulum, proximal magnum, distal magnum, isthmus, shell gland, and vagina. The drugs were added cumulatively. Only in the magnum did isoprenaline cause a significant change in the frequency of spike discharges; the decrease was about 20%. The effects of phenylephrine were not so clear, although the frequency of the electrical activity increased 30% in the shell gland. With the exception of the infundibulum, carbachol significantly increased the frequency of the oviductal electrical activity. It was concluded that adrenergic nerves have only a minor role in controlling quail oviductal smooth muscle because the oviduct was rather insensitive to adrenergic drugs whereas the cholinergic drug carbachol caused a strong response.

摘要

研究了分离的完整输卵管不同节段对异丙肾上腺素、去氧肾上腺素和卡巴胆碱的反应。使用吸力电极记录平滑肌电活动,每个电极分别置于漏斗部、近端壶腹部、远端壶腹部、峡部、壳腺和阴道。药物累积添加。仅在壶腹部,异丙肾上腺素使锋电位发放频率发生显著变化,降低约20%。去氧肾上腺素的作用不太明显,尽管壳腺中电活动频率增加了30%。除漏斗部外,卡巴胆碱显著增加了输卵管电活动频率。得出的结论是,肾上腺素能神经在控制鹌鹑输卵管平滑肌方面仅起次要作用,因为输卵管对肾上腺素能药物相当不敏感,而胆碱能药物卡巴胆碱则引起强烈反应。

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Adrenergic and cholinergic activity of the Japanese quail oviduct in vitro.日本鹌鹑输卵管体外的肾上腺素能和胆碱能活性
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