Kallman M J
Physiol Behav. 1983 Mar;30(3):431-5. doi: 10.1016/0031-9384(83)90149-x.
Partial destruction of the superior colliculus (45%) significantly decreased the normal facilitatory effect of ambient white noise on locomotor activity levels in young rats. As recovery from surgery occurred and as test experience increased, the loss observed immediately following surgery was reduced. Presumably because of the age of the rats examined, destruction of the superior colliculus failed to potentiate the stimulant effects of d-amphetamine or methylphenidate on locomotion. These data suggest that the superior colliculus is involved in changes in general activity that result from manipulation of auditory stimuli in the environment in addition to the documented involvement of the superior colliculus in alterations of general responsivity resulting from manipulations of visual stimuli in the environment. Moreover, the superior colliculus is implicated in maintaining both excitatory and inhibitory changes in response to the environment of the organism.
上丘部分损毁（45%）显著降低了环境白噪声对幼鼠运动活动水平的正常促进作用。随着术后恢复以及测试经验的增加，术后即刻观察到的损伤有所减轻。推测由于所检查大鼠的年龄，上丘损毁未能增强右旋苯丙胺或哌甲酯对运动的兴奋作用。这些数据表明，除了已有文献记载的上丘参与环境视觉刺激操作引起的一般反应性改变外，上丘还参与环境听觉刺激操作引起的一般活动变化。此外，上丘与维持机体对环境反应的兴奋性和抑制性变化有关。
