Foster C A, Aston S J
Plast Reconstr Surg. 1983 Jul;72(1):74-8. doi: 10.1097/00006534-198307000-00017.
Presented here are six examples of potentially life-threatening propranolol-epinephrine interactions. The only report found that warns of a deleterious clinical interaction between propranolol and epinephrine appeared in 1980. With widespread use of propranolol for approved and unapproved conditions, the population at risk is significant. All physicians and dentists using local anesthetic with epinephrine should be aware of this interaction.
这里展示了六种可能危及生命的普萘洛尔 - 肾上腺素相互作用的例子。唯一一份警告普萘洛尔和肾上腺素之间存在有害临床相互作用的报告发表于1980年。随着普萘洛尔在获批和未获批情况下的广泛使用，面临风险的人群数量众多。所有使用含肾上腺素局部麻醉剂的医生和牙医都应知晓这种相互作用。
