[气体低氧混合物GHM - 10对大鼠和人类皮肤多次照射的辐射防护作用]
[Radioprotective action of a gas hypoxic mixture GHM-10 in multiple irradiations of rat and human skin].
作者信息
Strelkov R B, Chizhov A Ia, Tokarev O Iu, Tolstykh V N, Kucherenko N G
出版信息
Radiobiologiia. 1983 May-Jun;23(3):358-62.
PMID:6867276
Abstract
Gas hypoxic mixture (GHM-10) decreased significantly the occurrence and duration of radioepidermitis after local therapeutic fractionated irradiation of Wistar rat skin with a cumulative dose of 66 Gy. In patients subjected to radiation therapy and protected with GHM-10 erythema and epidermitis developed at a much higher cumulative dose than in the controls. With erythema dose modifying coefficient was 1.38 +/- 0.06.
摘要
气体低氧混合物（GHM - 10）显著降低了Wistar大鼠皮肤局部分次照射累计剂量达66 Gy后放射性皮炎的发生率和持续时间。在接受放射治疗并用GHM - 10进行防护的患者中，红斑和皮炎出现时的累积剂量比对照组高得多。红斑剂量修正系数为1.38±0.06。
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