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患有先天性异常的婴儿与母乳中钼、砷、锰、锌和铜的含量

Infants with a congenital anomaly and the concentration of Mo, As, Mn, Zn and Cu in the mother's milk.

作者信息

Dang H S, Jaiswal D D, Wadhwani C N, Somasunderam S, Dacosta H

出版信息

Sci Total Environ. 1983 Mar;27(1):43-7. doi: 10.1016/0048-9697(83)90121-3.

DOI:10.1016/0048-9697(83)90121-3
PMID:6867706
Abstract

Thirty-one samples of mothers' milk were analysed by neutron activation analysis for the concentrations of Mo, As, Mn, Zn, Cu 1.5 to 3 months post-partum. Group I consisted of 6 mothers having infants with neonatal obstructive jaundice and exhibited lower mean values of Cu and Mn at 0.18 microgram/g and 11.7 micrograms/g as compared with 16 control subjects with 0.34 microgram/g Cu and 23.0 micrograms/g Mn;Mo levels were approximately twice as high (12.2 micrograms/g) as the control values (6.4 micrograms/g); Zn and As were grossly comparable. Group II consisted of 9 mothers who had delivered infants with either a congenital hydrocephalus (n = 7) or meningomyelocoele (n = 2), exhibited a mean Cu level of 0.27 microgram/g, Zn 1.7 micrograms/g, Mn 25.3 micrograms/g and As 0.45 microgram/g. These findings are discussed in the light of the patho-physiology of the congenital anomaly of the infant.

摘要

采用中子活化分析法对31份产后1.5至3个月的母乳样本进行了钼、砷、锰、锌、铜浓度分析。第一组由6名母亲组成,她们的婴儿患有新生儿梗阻性黄疸,与16名对照受试者相比,铜和锰的平均值较低,分别为0.18微克/克和11.7微克/克,而对照受试者的铜为0.34微克/克,锰为23.0微克/克;钼水平约为对照值(6.4微克/克)的两倍(12.2微克/克);锌和砷大致相当。第二组由9名母亲组成,她们分娩的婴儿患有先天性脑积水(7例)或脊髓脊膜膨出(2例),铜的平均水平为0.27微克/克,锌为1.7微克/克,锰为25.3微克/克,砷为0.45微克/克。根据婴儿先天性异常的病理生理学对这些发现进行了讨论。

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