Sasaki R, Kurokawa T, Kobayasi T, Tero-Kubota S
Tohoku J Exp Med. 1983 May;140(1):97-104. doi: 10.1620/tjem.140.97.
The concentrations of total ascorbic acid, reduced and oxidized forms of ascorbic acid, the ESR intensity of ascorbate radical, and the ratio of oxidized form of ascorbic acid to total ascorbic acid (DAsA/AsA) were estimated on 217 healthy controls, whose ages ranged from 12 to 96 years, in order to examine influences of sex and age. The concentration of total ascorbic acid was higher in females than in males throughout all age classes, but the oxidized form did not show a sex difference. Then it was found that the reduced form was higher in females than in males throughout all age classes. The concentrations of total ascorbic acid and reduced and oxidized forms of ascorbic acid, and the ESR intensity declined with age, but the DAsA/AsA ratio increased with age.
为了研究性别和年龄的影响，对217名年龄在12岁至96岁之间的健康对照者测定了总抗坏血酸、抗坏血酸的还原型和氧化型浓度、抗坏血酸自由基的电子自旋共振（ESR）强度以及抗坏血酸氧化型与总抗坏血酸的比值（DAsA/AsA）。在所有年龄组中，女性的总抗坏血酸浓度均高于男性，但氧化型抗坏血酸浓度无性别差异。随后发现，在所有年龄组中，女性的还原型抗坏血酸浓度均高于男性。总抗坏血酸以及抗坏血酸还原型和氧化型的浓度，还有ESR强度均随年龄下降，但DAsA/AsA比值随年龄增加。
