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人类正常皮肤菌群中的葡萄球菌。多种生物型和抗菌谱,无直接相关性。

Staphylococci of the normal human skin flora. Variety of biotypes and antibiograms without direct correlations.

作者信息

Hartmann A A

出版信息

Arch Dermatol Res. 1978 May 31;261(3):295-302. doi: 10.1007/BF00455299.

Abstract

352 strains of Staphylococci of the normal human skin flora were sampled from one volunteer by single scrabbing in a ca. 3 cm2 measuring area. They were biotyped by the scheme of Pelzer et al.(1973)--a modified Baird-Parker-Scheme (1963)--and the resistance to antibiotics was investigated by the method of Bauer et al. (1966). All the nine biotypes of Staphylococci were found in variable quantities. It seems problematic to call one biotype as the main type. Morphologically identical colonies of Staphylococci from the indigenous flora of the human skin were not identical in their biotypes as previously described by Pelzer (1976). Only the investigation of all Staphylococci colonies from the culture plate can evaluate all biotypes of Staphylococci of the normal human skin flora, and can give the right quantitative correlation. Staphylococci were found to be sensitive and resistant up to four antibiotics, and one biotype did not show one type of antibiogram.

摘要

通过单次刮擦,在约3平方厘米的测量区域内从一名志愿者身上采集了352株正常人体皮肤菌群中的葡萄球菌。按照Pelzer等人(1973年)的方案——一种改良的Baird - Parker方案(1963年)——对它们进行生物分型,并采用Bauer等人(1966年)的方法研究其对抗生素的耐药性。发现葡萄球菌的所有九种生物型数量各不相同。将一种生物型称为主要类型似乎存在问题。如Pelzer(1976年)之前所描述的,来自人体皮肤固有菌群的形态相同的葡萄球菌菌落,其生物型并不相同。只有对培养平板上的所有葡萄球菌菌落进行研究,才能评估正常人体皮肤菌群中葡萄球菌的所有生物型,并能给出正确的定量相关性。发现葡萄球菌对多达四种抗生素敏感或耐药,并且有一种生物型没有表现出一种类型的抗菌谱。

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