正常受试者中尿酸与钾的关系。
The relationship between uric acid and potassium in normal subjects.
作者信息
Kennedy A C, Boddy K, King P C, Brennan J, Anderson J A, Buchanan W W
出版信息
Ann Rheum Dis. 1978 Aug;37(4):333-8. doi: 10.1136/ard.37.4.333.
The serum uric acid concentration in normal healthy subjects has been studied in relation to sex, height, weight, lean body mass measured from total body potassium and predicted from the Hume-Weyers formula (1971), total body potassium, plasma potassium and urea, and packed cell volume. The strongest correlation was found with sex, but height, weight, total body potassium, lean body mass (measured and predicted) also correlated significantly with serum uric acid concentration. However, when the sex variable was removed, the other factors lost their significant correlation. Finally, total red blood cell and plasma volumes were predicted (Hume and Goldberg, 1964) and from these an estimate of total plasma uric acid, total plasma potassium, and total red blood cell potassium obtained. Measured total body potassium was found to correlate well with total plasma potassium and total red blood cell potassium independent of sex. Total plasma uric acid correlated well with measured total body potassium when both sexes were considered and when separated into male and female groups the males retained a significant correlation as did the female group.
对正常健康受试者的血清尿酸浓度进行了研究，涉及性别、身高、体重、通过全身钾含量测量并根据休谟 - 韦耶斯公式（1971年）预测的瘦体重、全身钾、血浆钾和尿素以及红细胞压积。发现与性别相关性最强，但身高、体重、全身钾、瘦体重（测量值和预测值）也与血清尿酸浓度显著相关。然而，当去除性别变量时，其他因素失去了显著相关性。最后，预测了总红细胞和血浆体积（休谟和戈德堡，1964年），并据此获得了总血浆尿酸、总血浆钾和总红细胞钾的估计值。发现测量的全身钾与总血浆钾和总红细胞钾密切相关，且与性别无关。当考虑两性时，总血浆尿酸与测量的全身钾密切相关，当分为男性和女性组时，男性和女性组均保持显著相关性。
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