Krempler F, Asamer H, Bolzano K, Sandhofer F
Acta Med Austriaca. 1983;10(1):31-4.
Course and treatment of a case of Wegener's granulomatosis are reported. A 39-year-old man admitted to the hospital because of abnormal densities demonstrated by the X-ray examination of the chest. The patient developed a rapidly progressive renal failure with renal insufficiency. Diagnosis was obtained by biopsys from the upper respiratory tract and from the kidney. During hemodialysis and immunosuppressive therapy renal function improved and hemodialysis could be stopped. The patient was discharged from the hospital and kept on immunosuppressive therapy. The patient omitted the medication by himself and renal insufficiency reappeared. The disease was progressive and the patient died because of intestinal bleeding. Apart from the description of the symptoms of this rare disease, problems of diagnosis and treatment are discussed.
报告了一例韦格纳肉芽肿病的病程及治疗情况。一名39岁男性因胸部X线检查显示异常密度影而入院。患者出现快速进展性肾衰竭并伴有肾功能不全。通过对上呼吸道和肾脏进行活检得以确诊。在血液透析和免疫抑制治疗期间,肾功能有所改善,血液透析得以停止。患者出院后继续接受免疫抑制治疗。但患者自行停药,肾功能不全再次出现。病情呈进行性发展,患者最终因肠道出血死亡。除了对这种罕见疾病的症状进行描述外,还讨论了诊断和治疗方面的问题。