锂盐治疗组和非锂盐治疗组躁郁症患者的消化性溃疡主诉

Peptic ulcer complaints in lithium-treated and non-lithium-treated manic-depressive patients.

作者信息

Jepsen P W, Jensen E, Plenge P, Rafaelsen O J

出版信息

Acta Psychiatr Scand. 1983 May;67(5):358-60. doi: 10.1111/j.1600-0447.1983.tb00353.x.

DOI:10.1111/j.1600-0447.1983.tb00353.x

Abstract

A possible protective effect of lithium against the occurrence of peptic ulcer complaints in manic-depressive patients, treated with lithium, was investigated. 167 manic-depressive patients, 91 in lithium treatment, 76 not in lithium treatment, were questioned about clinical symptoms of peptic ulcer. Thirteen of the lithium-treated and 23 of the non-lithium-treated patients reported symptoms of peptic ulcer. The difference was statistically significant. The hypothesis that lithium treatment reduces the frequency of symptoms of peptic ulcer in manic-depressive patients was thus confirmed.

摘要

对锂盐治疗的躁郁症患者中锂盐预防消化性溃疡发生的可能保护作用进行了研究。167名躁郁症患者，其中91名接受锂盐治疗，76名未接受锂盐治疗，被询问有关消化性溃疡的临床症状。接受锂盐治疗的患者中有13人，未接受锂盐治疗的患者中有23人报告有消化性溃疡症状。差异具有统计学意义。因此，锂盐治疗可降低躁郁症患者消化性溃疡症状发生率这一假设得到了证实。