Pimenta J, Miranda M, Pereira C B
Am Heart J. 1983 Aug;106(2):374-80. doi: 10.1016/0002-8703(83)90206-5.
Under electrophysiologic studies, 44 asymptomatic chagasic individuals were studied. The mean age was 39.9 years, with 26 being male. The surface ECG showed normal tracings in 12 patients, left anterior fascicular block in three, incomplete right bundle branch block in two, and right bundle branch block in 27 (isolated in six, associated with left anterior fascicular block in 19 and with left posterior fascicular block in two). Sinus nodal dysfunction was found in eight (18.1%), and 29 (66%) presented with some form of abnormal AV nodal behavior during atrial stimulation. Repetitive ventricular beats were recorded in 17 (41.4%) patients. Finally, in 19 (43.1%), patterns of dysfunction at two or more levels of the cardiac conducting system were found. It is concluded that the chagasic cardiomyopathy produces diffuse lesions in the conducting tissue of the human heart in the stages when the disease is detected, and that the individuals are still asymptomatic.
在电生理研究中,对44名无症状恰加斯病患者进行了研究。平均年龄为39.9岁,其中26名为男性。体表心电图显示,12例患者心电图正常,3例有左前分支阻滞,2例有不完全性右束支阻滞,27例有右束支阻滞(6例为孤立性,19例合并左前分支阻滞,2例合并左后分支阻滞)。8例(18.1%)发现窦房结功能障碍,29例(66%)在心房刺激时出现某种形式的房室结异常表现。17例(41.4%)患者记录到反复性室性搏动。最后,19例(43.1%)在心脏传导系统的两个或更多水平发现功能障碍模式。得出的结论是,恰加斯病性心肌病在疾病被检测出的阶段,会在人体心脏的传导组织中产生弥漫性病变,且这些个体仍无症状。