Baum D, Beck R Q, Haskell W L
Am J Cardiol. 1983 Aug;52(3):349-52. doi: 10.1016/0002-9149(83)90137-6.
The effects of systemic-pulmonary artery shunts on growth, body composition, and adipose tissue were studied in 29 children, aged 2 to 16 years, with cyanotic congenital heart disease. Of these, 16 received surgical shunts and 13 were unoperated. Postoperatively, all patients who received shunts were better oxygenated (systemic oxygen saturation 69 +/- 11% preoperatively and 84 +/- 4% postoperatively; mean +/- standard error of the mean) and were symptomatically improved. However, the groups were not significantly different in height, weight, lean body mass, total body fat, lean/fat ratio, cellular lipid content, or total number of lipid-containing fat cells. Age at operation did not seem to influence the effects of surgery. These observations suggest that growth and certain measurements of tissue development were unaffected by surgical systemic-pulmonary artery shunts despite increased oxygenation and symptomatic improvement after operation.
对29名年龄在2至16岁之间的患有青紫型先天性心脏病的儿童，研究了体-肺动脉分流术对生长、身体成分和脂肪组织的影响。其中，16名接受了手术分流，13名未接受手术。术后，所有接受分流的患者氧合状况均有所改善（术前体循环血氧饱和度为69±11%，术后为84±4%；均值±均值标准误差），症状也有所改善。然而，两组在身高、体重、瘦体重、全身脂肪、瘦/脂比、细胞脂质含量或含脂质脂肪细胞总数方面并无显著差异。手术时的年龄似乎并未影响手术效果。这些观察结果表明，尽管术后氧合增加且症状改善，但手术性体-肺动脉分流术并未影响生长及组织发育的某些测量指标。
