Rubin J, Kvols L K, Moertel C G, Jones A R, Hahn R G, O'Connell M J
Am J Clin Oncol. 1983 Aug;6(4):477-9. doi: 10.1097/00000421-198308000-00015.
A phase II study of ADAH was conducted in thirty patients with biopsy-prove metastatic or recurrent colorectal carcinoma in order to define its benefits and toxicity. Doses were adjusted by leukocyte nadirs. No patients met the criteria for complete or partial response.