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大鼠在没有新皮层的情况下对音调分心的习惯化。

Habituation of distraction to a tone in the absence of neocortex in rats.

作者信息

Yeo A G, Oakley D A

出版信息

Behav Brain Res. 1983 Jun;8(3):403-9. doi: 10.1016/0166-4328(83)90184-5.

DOI:10.1016/0166-4328(83)90184-5
PMID:6871024
Abstract

Normal rats and rats with in excess of 95% of neocortex surgically removed (decorticated) were trained to push a food tray door on a Fixed Ratio schedule. Once the behaviour was established a 3720 Hz, 70 dB tone was presented 4 times per session and the duration of distraction from the operant baseline was recorded. Both groups of rats habituated to the presence of the tone within a single session and the effects were retained over a 24 h interval. The decorticates, but not the normal animals, showed a partial spontaneous recovery of the habituated response between sessions. It was concluded that neocortex is not required for either short-term or long-term habituation in this situation though long-term habituation is more complete when neocortex is present.

摘要

正常大鼠以及手术切除超过95%新皮层(去皮质)的大鼠,按照固定比率程序接受训练以推开食物托盘门。一旦行为建立起来,每次训练中会呈现4次频率为3720赫兹、强度为70分贝的音调,并记录偏离操作性基线的分心持续时间。两组大鼠在单次训练中都对音调的出现产生了习惯化,且这种效果在24小时的间隔内得以保持。去皮质大鼠,但正常动物没有,在各次训练之间表现出习惯化反应的部分自发恢复。得出的结论是,在这种情况下,短期或长期的习惯化都不需要新皮层,尽管存在新皮层时长期习惯化会更完整。

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