非洲爪蟾红细胞内源性的一种钙激活核酸酶。
A calcium-activated nuclease endogenous to Xenopus erythrocytes.
作者信息
Talwar S, Pocklington M J, Maclean N
出版信息
FEBS Lett. 1983 Jul 25;158(2):349-52. doi: 10.1016/0014-5793(83)80611-5.
PMID:6873288
Abstract
An endogenous nuclease is found in purified Xenopus erythrocyte nuclei. This enzyme is activated specifically by Ca2+ in the presence of which chromatin is digested into discrete fragments. Both 10 bp and 200 bp ladders are detected upon electrophoresis of DNA. This endogenous enzyme therefore resembles mammalian and chicken liver endonucleases.
摘要
在纯化的非洲爪蟾红细胞核中发现了一种内源性核酸酶。这种酶在Ca2+存在下被特异性激活，在此条件下染色质被消化成离散的片段。对DNA进行电泳时可检测到10 bp和200 bp的梯状条带。因此，这种内源性酶类似于哺乳动物和鸡肝中的核酸酶。
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