An interim report of flurbiprofen for the control of idiopathic hypercalciuria.

Twenty patients with idiopathic hypercalciuria were entered into an 8 week open study to examine the effects of flurbiprofen 50 mg three times a day on urinary calcium excretion. Five patients had to be withdrawn because of side-effects. A statistically significant reduction in urinary calcium excretion was seen after 2 (p = 0.01) and 6 (p = 0.008) weeks treatment. The results suggest that flurbiprofen may be a useful alternative for the treatment of this disorder. The 25% of patients withdrawn due to side-effects may be a limiting factor.