White C T, White C L, Hintze R W
Int J Neurosci. 1983 May;19(1-4):133-41. doi: 10.3109/00207458309148650.
It has been well established that there is a reliable implicit time to the VEP positive component (ca 100 msec) in response to pattern reversal. This has become a valuable test of the status of the visual system. Recent data suggest that activity around 200 msec is another useful measure of the cortical response to pattern alternation. We have carried out a normative study of the relative amplitudes of the two components. Among adults with normal visual acuity activity around 200 msec is directly related to the spatial frequency of the stimulus, peaking markedly in amplitude at a narrow range of spatial frequencies. This is in sharp contrast to the earlier component, which does not exhibit such sensitive size differentiation. Recently we have used the ratio between the late and early component amplitudes as a quantitative indicator of the efficiency of higher-level processing of pattern information. We present our normative data and illustrate the effects of decreased visual responses not related to known peripheral optical problems. The results of this work are also interpreted as showing basic characteristics of information processing in the visual system, in that higher spatial frequencies are processed by a continuum of rather sharply tuned cortical processes, with the higher spatial frequencies being processed later in time.
已有充分证据表明，在对模式翻转的视觉诱发电位（VEP）正波成分（约100毫秒）存在一个可靠的隐含时间。这已成为视觉系统状态的一项重要测试。最近的数据表明，200毫秒左右的活动是对模式交替的皮质反应的另一项有用指标。我们对这两个成分的相对振幅进行了一项规范性研究。在视力正常的成年人中，200毫秒左右的活动与刺激的空间频率直接相关，在一个狭窄的空间频率范围内振幅显著达到峰值。这与早期成分形成鲜明对比，早期成分并未表现出如此敏感的大小差异。最近我们使用晚期和早期成分振幅之间的比率作为模式信息高级处理效率的定量指标。我们展示了我们的规范性数据，并说明了与已知周边光学问题无关的视觉反应降低的影响。这项工作的结果也被解释为显示了视觉系统中信息处理的基本特征，即较高的空间频率由一系列相当尖锐调谐的皮质过程进行处理，较高的空间频率在时间上处理得较晚。
