Civatte J
Hautarzt. 1983 Jun;34(6):298-305.
This review deals with the lesions of the genitalia histologically mimicking Bowen's disease, yet behaving like a benign process. The report is based on data from the literature and on 14 personal cases, four of which are described here as examples. Some of the cases, mostly young patients, showed spontaneous regression; in others condylomata acuminata developed on the site of the lesions; in rare instances a "transformation" in lichen planus occurred. For these not really precancerous conditions the at present most widely accepted name is bowenoid papulosis. As far as etiology is concerned, the responsibility of human papilloma virus is generally accepted or considered likely, although there are only very few cases when the virus has really been evidenced. Diagnosis of a pseudo-Bowen's disease can only be made after clinico-pathologic correlation. A careful follow-up is necessary if it has been decided not to destroy the lesion.
本综述探讨了组织学上模仿鲍温病但表现为良性过程的生殖器病变。该报告基于文献数据和14例个人病例,其中4例在此作为示例进行描述。部分病例,大多为年轻患者,病变出现自发消退;其他病例在病变部位发展为尖锐湿疣;罕见情况下会出现扁平苔藓的“转变”。对于这些并非真正癌前病变的情况,目前最广泛接受的名称是鲍温样丘疹病。就病因而言,人乳头瘤病毒的作用已得到普遍认可或被认为很有可能,尽管仅有极少数病例真正证实了该病毒的存在。假性鲍温病的诊断只能在临床病理关联后做出。如果决定不破坏病变,则需要进行仔细的随访。