Tanada S
Nihon Sanka Fujinka Gakkai Zasshi. 1983 Jul;35(7):960-6.
The effect of electrical stimulation on hypothalamic nuclei was studied by using a stereotaxic operation and in vitro bioassay of luteinizing hormone (LH) in the macaca fuscata. The results were as follows: The serum LH level was increased when the arcuate nucleus or the ventromedial nucleus was stimulated at 250 mu A and 500 mu A. The serum LH level was not increased when the paraventricular nucleus or supraoptic nucleus was stimulated at 250 mu A and 500 mu A. When the medial preoptic nucleus was stimulated at 250 mu A, the serum LH level was not increased. However, the stimulation of 500 mu A increased the serum LH level. The stimulation of the lateral preoptic nucleus did not increase the serum LH at 250 mu A and 500 mu A. The half lives of LH were 35.4 min., 33.4 min., 48.4 min., 43.1 min. These results were different from the half life of human LH. The contribution of various hypothalamic nuclei to the release of LH was discussed.
采用立体定位手术和食蟹猴促黄体生成素（LH）体外生物测定法，研究了电刺激对下丘脑核团的影响。结果如下：当以250微安和500微安刺激弓状核或腹内侧核时，血清LH水平升高。当以250微安和500微安刺激室旁核或视上核时，血清LH水平未升高。当以250微安刺激视前内侧核时，血清LH水平未升高。然而，500微安的刺激可使血清LH水平升高。以250微安和500微安刺激视前外侧核时，血清LH水平未升高。LH的半衰期分别为35.4分钟、33.4分钟、48.4分钟、43.1分钟。这些结果与人LH的半衰期不同。文中讨论了各种下丘脑核团对LH释放的作用。
