Guilbeau J C, Frija J, Gluckman E, Verola O, Brocheriou C, Laval-Jeantet M
J Radiol. 1983 May;64(5):347-51.
The case of a 42 years old man who had a monoblastic acute leukemia treated by a bone-marrow graft is described. The patient died of a cerebral toxoplasmosis and a cerebral computed tomography done two days before is correlated with anatomopathologic slices done in the same planes than the computed tomagraphy examination. There is a good correlation between necrotic abceded areas and hypodense areas accompanied by serpiginous fixations of contrast media. The immunocompromised patient is very favorable for the development of a cerebral toxoplasmosis. CT, while not specific, has the advantage to suspect the diagnosis which must be discussed with other oportunistic infections, leukemic infiltrates, methotrexate encephalopathy, progressive multifocal encephalopathy, and small infarcts.
描述了一名42岁患有单核细胞性急性白血病并接受骨髓移植治疗的男性病例。患者死于脑弓形虫病,且对其死亡前两天进行的脑部计算机断层扫描与在与计算机断层扫描检查相同平面上进行的解剖病理切片进行了对比。坏死脱落区域与低密度区域以及造影剂的蜿蜒状固定之间存在良好的相关性。免疫功能低下的患者非常容易发生脑弓形虫病。计算机断层扫描虽然不具有特异性,但具有怀疑诊断的优势,必须与其他机会性感染、白血病浸润、甲氨蝶呤脑病、进行性多灶性白质脑病和小梗死进行鉴别诊断。