Dawson J, Bloom S R, Cockel R
Postgrad Med J. 1983 May;59(691):315-6. doi: 10.1136/pgmj.59.691.315.
A patient is described who presented with a 10 year history of intermittent peptic ulcer symptoms and a 3 year history of an undiagnosed skin rash. Investigations indicated raised plasma levels of gastrin, glucagon and pancreatic polypeptide. A single tumour was localised to the pancreas and resected. The tumour had the typical histology of an apudoma, and contained cells which stained for gastrin, glucagon, pancreatic polypeptide and neurotensin.
本文描述了一名患者,其有10年间歇性消化性溃疡症状病史及3年未确诊的皮疹病史。检查显示血浆胃泌素、胰高血糖素和胰多肽水平升高。发现胰腺有一个单一肿瘤并进行了切除。该肿瘤具有典型的APUD瘤组织学特征,且含有对胃泌素、胰高血糖素、胰多肽和神经降压素染色的细胞。