Goriaev P P, Vikhert A M, Zakharkina G A
Biull Eksp Biol Med. 1978 Aug;86(8):170-2.
Biosynthesis of reserpine-like substances with participation of such radioactive precursors as formiate, methyl groups of S-adenosylmethionine, tryptophane, reserpine, etc. occurred in the homogenates, microsomes, and cytozol of different human and animal tissues. As suggested, endogenous reserpine-like substances participated in the autoregulation of free and bound biogenic amines level.
在不同人类和动物组织的匀浆、微粒体及胞质溶胶中,存在着以甲酸、S-腺苷甲硫氨酸的甲基基团、色氨酸、利血平等等放射性前体参与的利血平样物质的生物合成。据推测,内源性利血平样物质参与了游离和结合生物胺水平的自动调节。