Barsotti G, Morelli E, Guiducci A, Giannoni A, Ciardella F, Niosi F, Lupetti S, Giovannetti S
Proc Eur Dial Transplant Assoc. 1983;19:773-8.
A low nitrogen, low phosphorus diet, supplemented with essential amino acids and keto-analogues, was administered to 48 chronic uraemics for a maximum of 36 months. In 10 cases renal function deteriorated and dialysis was started; eight patients changed to the dialytic therapy having difficulties in complying to the diet and three died for reasons not directly related to renal failure. The remaining twenty-seven patients are still on dietetic treatment and their renal function has not changed significantly. Their serum inorganic phosphorus and their circulating iPTH decreased significantly. Their subjective and objective conditions are satisfactory and no manifestation of protein malnutrition or other unwanted effects are detectable.
对48例慢性尿毒症患者采用低氮、低磷饮食，并补充必需氨基酸和酮类似物，最长持续36个月。10例患者肾功能恶化并开始透析；8例患者因难以坚持饮食改为透析治疗，3例患者因与肾衰竭无直接关系的原因死亡。其余27例患者仍在接受饮食治疗，其肾功能无明显变化。他们的血清无机磷和循环iPTH显著降低。他们的主观和客观状况良好，未检测到蛋白质营养不良或其他不良影响的表现。
