Palmaz J C, Hunter G, Carson S N, French S W
Radiology. 1983 Sep;148(3):699-702. doi: 10.1148/radiology.148.3.6878688.
Following endarterectomy, stenosis can recur in 0.2-3.6% of carotid arteries due to neointimal fibromuscular hyperplasia (NFH). Angiographically, NFH is manifested as concentric, alternating areas of normal tissue and smooth narrowing which are seen as pale, glistening, nonulcerated plaques on gross examination. Histological study demonstrates proliferation of smooth muscle cells, disruption of the internal elastic lamina, and often discontinuity of the endothelium. Calcium and cholesterol deposits are absent. The cause of the lesion is unknown, and surgical management is frequently difficult.
动脉内膜切除术后，由于新生内膜纤维肌肉增生（NFH），0.2%-3.6%的颈动脉会出现狭窄复发。在血管造影中，NFH表现为正常组织与平滑狭窄交替出现的同心区域，在大体检查中表现为苍白、有光泽、无溃疡的斑块。组织学研究显示平滑肌细胞增殖、内弹性膜破坏，且内皮通常不连续。无钙和胆固醇沉积。该病变的病因不明，手术治疗常常很困难。
