The role of surgery, radio- and chemotherapy in the treatment of neuroblastoma and ganglioneuroblastoma.

Personal experiences with biochemical assessments of the urinary catecholamine metabolite excretion in 460 patients with neuroblastoma and 55 patients with ganglioneuroblastoma, as well as prognostic factors and selected data characterizing the role of surgery, radio- and chemotherapy in the treatment of neuroblastoma are reviewed. Recommendations regarding optimal combinations of the 3 treatment modalities are made, taking into account age and stage.