Burckhardt D
Schweiz Med Wochenschr. 1983 May 21;113(20):746-9.
The problems of digitalis therapy are closely related to the intoxication rate of 10-20% in patients under longterm treatment. Awareness of the problems occurring in digitalis therapy should result in a decrease in the intoxication rate. This can be accomplished by (1) information to the patient and (2) information to the physician regarding the pitfalls of digitalis therapy. In this context reference will be made to therapeutic range, mode of digitalization, absorption, conditions associated with decreased digitalis tolerance, conditions involving increased need of digitalis, conditions associated with decreased need for digitalis, and drug interactions.
洋地黄疗法的问题与长期治疗患者中10%-20%的中毒率密切相关。认识到洋地黄疗法中出现的问题应能降低中毒率。这可以通过以下方式实现:(1)向患者提供信息;(2)向医生提供有关洋地黄疗法陷阱的信息。在此背景下,将提及治疗范围、洋地黄化模式、吸收、与洋地黄耐受性降低相关的情况、洋地黄需求增加的情况、与洋地黄需求减少相关的情况以及药物相互作用。