1976 - 198年南威尔士和西威尔士粟粒性肺结核治疗的回顾性调查
Retrospective survey of the management of miliary tuberculosis in South and West Wales, 1976-8.
作者信息
Monie R D, Hunter A M, Rocchiccioli K M, White J P, Campbell I A, Kilpatrick G S
出版信息
Thorax. 1983 May;38(5):369-72. doi: 10.1136/thx.38.5.369.
In a survey of 1000 patients with tuberculosis 28 were found to have miliary disease. Half of these patients were over 60 years old. Anorexia and weight loss were present in 19 (70%) and pyrexia in 17 (63%). A factor predisposing to tuberculosis or a history of recent contact was found in 12 (43%), and 21 (75%) had positive cultures. Seventeen (61%) had classical miliary shadowing while four (14%) had cryptic miliary tuberculosis with no radiological evidence of tuberculosis. The remaining seven patients (25%) had radiological changes consistent with pulmonary tuberculosis, but no miliary shadows. Of those who completed chemotherapy, only five (42%) received 18 months' treatment. Nine patients (32%) died from their miliary tuberculosis. Failure to consider the diagnosis, leading to a delay in starting chemotherapy, appeared to be a major problem.
在一项对1000例肺结核患者的调查中，发现28例患有粟粒性疾病。这些患者中有一半年龄超过60岁。19例（70%）出现厌食和体重减轻，17例（63%）出现发热。12例（43%）发现有易患结核病的因素或近期接触史，21例（75%）培养结果呈阳性。17例（61%）有典型的粟粒样阴影，而4例（14%）有隐匿性粟粒性肺结核，无肺结核的放射学证据。其余7例患者（25%）有与肺结核相符的放射学改变，但无粟粒样阴影。在完成化疗的患者中，只有5例（42%）接受了18个月的治疗。9例患者（32%）死于粟粒性肺结核。未考虑该诊断导致化疗开始延迟，这似乎是一个主要问题。
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