de Vries P J, van der Holst W
Tijdschr Diergeneeskd. 1983 May 15;108(10):401-6.
The reliability of determination of the plasma progesterone level within approximately eighteen days after ovulation in the pregnancy diagnosis of mares is examined in the present study. Studies were done in seventy-five mares, a number of which were served or inseminated during several cycles so that a total number of eighty-seven blood samples were obtained. On the analogy of other authors, the progesterone level above which mares were believed to be pregnant and below which they were assumed to be non-pregnant, was set at 2 ng/ml. The twenty-five mares in which the level was below 2 ng/ml. were indeed found to be non-pregnant at that time of examination, the levels of six samples not being determined in view of the predictable results. Of the sixty mares showing progesterone levels of more than 2 ng/ml., forty-seven were ultimately found te be pregnant, fifty-five had probably been pregnant on day 18 and five were non-pregnant and had not been pregnant. The reliability of a diagnosis negative for pregnancy, based on determination of the progesterone level, was one hundred per cent in these cases, that of a diagnosis positive for pregnancy being 78.3 per cent. When early embryonal mortality was taken into account, reliability of a diagnosis positive for pregnancy was 91.6 per cent. Overall reliability was 84.7 per cent.
本研究检验了在母马妊娠诊断中,排卵后约18天内血浆孕酮水平测定的可靠性。对75匹母马进行了研究,其中一些母马在多个发情周期中接受配种或输精,共采集了87份血样。按照其他作者的类推,将母马被认为怀孕时的孕酮水平设定为2 ng/ml以上,低于此水平则假定为未怀孕。25匹母马的孕酮水平低于2 ng/ml,在检查时确实被发现未怀孕,鉴于结果可预测,6份样本的水平未测定。在60匹孕酮水平高于2 ng/ml的母马中,最终发现47匹怀孕,55匹在第18天可能已怀孕,5匹未怀孕且未曾怀孕。基于孕酮水平测定的妊娠阴性诊断的可靠性在这些病例中为100%,妊娠阳性诊断的可靠性为78.3%。当考虑早期胚胎死亡率时,妊娠阳性诊断的可靠性为91.6%。总体可靠性为84.7%。