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[气性坏疽]

[Gas gangrene].

作者信息

Gürtner T

出版信息

Unfallchirurgie. 1983 Jun;9(3):172-4.

PMID:6879847
Abstract

In spite of surgical, intensive, and hyperbaric oxygen therapy, the gas gangrene is still one of the most dangerous surgical infections. In recent literature, the average mortality is about 50%. The patients die within a few days because of general intoxication. A review of our own results achieved between 1971 and 1981 shows that 50 out of 73 patients with clostridium infection and all 77 patients in whom a gas gangrene was suspected have survived [ 2 ]. For the prognosis and therapy of the gas gangrene, the classification into stages I to IV according to the severity has proved to be useful. The prognosis depends on the incubation period (the shorter the incubation period the worse the prognosis), on the beginning of the treatment and on the site of a primary or secondary gas gangrene. The more distally the gas gangrene is situated in the extremities, the better is the prognosis with regard to mortality and invalidity. An early diagnosis of the gas gangrene is of primary importance. As early as a gas gangrene is suspected because of typical local findings and clinical symptoms, therapeutic measures are immediately necessary (surgery, intensive treatment and hyperbaric oxygen therapy). A transport of more than six hours with prolonged interruption of the treatment will decrease the chances of success even in a "gas gangrene therapy centre".

摘要

尽管采用了手术、强化治疗和高压氧治疗,气性坏疽仍是最危险的外科感染之一。在最近的文献中,平均死亡率约为50%。患者会因全身中毒在数天内死亡。回顾我们在1971年至1981年间取得的成果,发现73例梭菌感染患者中有50例存活,所有77例疑似气性坏疽的患者也均存活[2]。对于气性坏疽的预后和治疗,根据严重程度分为I至IV期已被证明是有用的。预后取决于潜伏期(潜伏期越短,预后越差)、治疗开始时间以及原发性或继发性气性坏疽的部位。气性坏疽在四肢的位置越靠远端,在死亡率和致残率方面的预后就越好。气性坏疽的早期诊断至关重要。一旦因典型的局部表现和临床症状怀疑气性坏疽,立即采取治疗措施(手术、强化治疗和高压氧治疗)就很有必要。即使在“气性坏疽治疗中心”,运输时间超过6小时且治疗长时间中断也会降低成功的几率。

相似文献

1
[Gas gangrene].[气性坏疽]
Unfallchirurgie. 1983 Jun;9(3):172-4.
2
Hyperbaric oxygen therapy in acute necrotizing infections with a special reference to the effects on tissue gas tensions.高压氧疗法在急性坏死性感染中的应用,特别提及对组织气体张力的影响。
Ann Chir Gynaecol Suppl. 2000(214):7-36.
3
Hyperbaric oxygen therapy in acute necrotizing infections. With a special reference to the effects on tissue gas tensions.急性坏死性感染中的高压氧疗法。特别提及对组织气体张力的影响。
Ann Chir Gynaecol. 2000;89 Suppl 214:7-36.
4
Hyperbaric oxygen in the treatment of gas gangrene and perineal necrotizing fasciitis. A clinical and experimental study.高压氧治疗气性坏疽和会阴坏死性筋膜炎:一项临床与实验研究
Eur J Surg Suppl. 1993(570):1-36.
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[Prerequisites for the transfer of patients with gas gangrene to a specialized facility].[气性坏疽患者转至专科医院的先决条件]
Anaesthesiol Reanim. 1991;16(1):49-58.
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Gas gangrene: potential for hyperbaric oxygen therapy.气性坏疽:高压氧治疗的潜力
Postgrad Med. 1996 Apr;99(4):217-20, 224.
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Treatment of gas gangrene. Interest of hyperbaric oxygen therapy.气性坏疽的治疗。高压氧疗法的作用。
Acta Anaesthesiol Belg. 1977 Mar;28(1):41-52.
8
Postoperative gas gangrene.术后气性坏疽
J Foot Surg. 1983 Summer;22(2):126-33.
9
Clostridium septicum infections in children: a case report and review of the literature.儿童败血梭菌感染:一例病例报告及文献综述
Pediatrics. 2006 Apr;117(4):e796-805. doi: 10.1542/peds.2005-1074. Epub 2006 Mar 27.
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[Hyperbaric oxygenation: utility in intensive therapy - part 2].[高压氧疗法:在重症治疗中的应用 - 第2部分]
Anasthesiol Intensivmed Notfallmed Schmerzther. 2009 Oct;44(10):652-8. doi: 10.1055/s-0029-1242433. Epub 2009 Oct 15.

引用本文的文献

1
[Gas gangrene of the hand. A case report].[手部气性坏疽。病例报告]
Unfallchirurgie. 1994 Aug;20(4):223-6. doi: 10.1007/BF02588716.