前列腺癌中的弥散性血管内凝血：雌激素治疗的作用
Disseminated intravascular coagulation in carcinoma of prostate: role of estrogen therapy.
作者信息
Goldenberg S L, Fenster H N, Perler Z, McLoughlin M G
出版信息
Urology. 1983 Aug;22(2):130-2. doi: 10.1016/0090-4295(83)90492-2.
PMID:6879882
Abstract
Advanced carcinoma of the prostate may present as disseminated intravascular coagulation and its sequelae. It is postulated that the slow release of thromboplastic material from tumor cells eventually overcomes normal homeostatic mechanisms. High-dose intravenous diethylstilbestrol diphosphate successfully reversed this coagulopathy in 2 cases of metastatic carcinoma of the prostate.
摘要
晚期前列腺癌可能表现为弥散性血管内凝血及其后遗症。据推测，肿瘤细胞缓慢释放促凝物质最终会打破正常的体内平衡机制。大剂量静脉注射己烯雌酚二磷酸酯成功逆转了2例前列腺转移癌患者的这种凝血病。
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