Vinokurova N A, Danova L A, Kondrat'ev V B, Gershanovich M L
Vopr Onkol. 1983;29(7):46-50.
Combined chemotherapy (prospidin, cyclophosphamide, vincristine and prednisolone) (PCVP) was given to 32 patients with recurrent generalized forms of Hodgkin's disease. Remission was reliably established in 75% of patients; its mean duration was 2.8 months. 15 patients received repeated courses of complex chemotherapy, including prospidin; it proved effective in 12 of them. Mean duration of remission was 2.7 months. Toxic side--effects were insignificant and subsided quickly. The results of the study point to the effectiveness of PCVP scheme application in patients with recurrent generalized forms of Hodgkin's disease.
对32例复发性全身性霍奇金病患者给予联合化疗(丙亚胺、环磷酰胺、长春新碱和泼尼松)(PCVP)。75%的患者可靠地实现了缓解;缓解的平均持续时间为2.8个月。15例患者接受了包括丙亚胺在内的重复多疗程化疗;其中12例证明有效。缓解的平均持续时间为2.7个月。毒副作用不明显且很快消退。该研究结果表明PCVP方案应用于复发性全身性霍奇金病患者是有效的。