Wünsche L, Kiesel B, Fischer H
Z Allg Mikrobiol. 1983;23(3):189-96. doi: 10.1002/jobm.3630230307.
The lysogenic state of the methylotrophic strain Acetobacter MB 58/1 is completely demonstrated by curing and lysogenization experiments. During these investigations we found that some phenotypic characteristics are modified by the presence or loss of the prophage MO 1. It could be shown that changes of the serological behaviour, the adsorption of the phages and the sensitivity against oxytetracycline are caused by lysogenic conversion. The phenotypic alterations of the bacterial cells induced by the phage genome are the result of modifications of the lipopolysaccharide structures on the cell surface. In the case of oxytetracycline resistance, interactions between the modified lipopolysaccharide structures and specific transport proteins of the cell membranes must be assumed.
通过消除和溶源化实验,充分证明了甲基营养型菌株醋酸杆菌MB 58/1的溶源状态。在这些研究中,我们发现某些表型特征会因原噬菌体MO 1的存在或缺失而发生改变。可以证明,血清学行为的变化、噬菌体的吸附以及对土霉素的敏感性是由溶源转化引起的。噬菌体基因组诱导的细菌细胞表型改变是细胞表面脂多糖结构修饰的结果。就土霉素抗性而言,必须假定修饰的脂多糖结构与细胞膜的特定转运蛋白之间存在相互作用。