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骨折创伤后最初24小时内闭合性小腿骨折的动物实验闪烁扫描研究

[Animal experimental scintigraphic studies of closed lower leg fractures during the 1st 24 hours following the fracture trauma].

作者信息

Klug W, Franke W G, Schulze M

出版信息

Z Exp Chir Transplant Kunstliche Organe. 1983;16(3):173-7.

PMID:6880324
Abstract

A closed fracture in the medium third part of the tibia was carried out in 50 rabbits. The scintigraphy was performed in groups of 5 animals at a time 2, 4, 6, 10, 12, 14, 16, 18, and 24 hours after the fracture trauma, in each case 45 minutes after the injection of 8 MBq 99mTc diphosphonat per kg body weight. The ROI activity quotient of both shank diaphysis was analysed. The first ascent was observed at the tenth postoperative hour. The ROI activity quotient was 2.1 24 hours after the fracture trauma. No marking of the fracture area was observed but an increase of the activity altogether above the diaphysis, and no ascent of the activity quotient in the neighbouring joints was observed.

摘要

对50只家兔造成胫骨中三分之一处闭合性骨折。在骨折创伤后2、4、6、10、12、14、16、18和24小时,每次对5只动物为一组进行骨闪烁显像,每种情况下在每千克体重注射8MBq 99mTc二膦酸盐后45分钟进行。分析双侧胫骨干骺端的感兴趣区(ROI)活性商。术后第10小时观察到首次活性上升。骨折创伤后24小时ROI活性商为2.1。未观察到骨折区域有放射性标记,但干骺端上方的活性总体增加,且未观察到相邻关节处活性商上升。

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