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[10例糖尿病患者的膜性肾小球肾炎]

[Membranous glomerulonephritis in 10 diabetics].

作者信息

Ditscherlein G, Schneider W

出版信息

Zentralbl Allg Pathol. 1983;127(3-4):245-51.

PMID:6880436
Abstract

Membranous glomerulonephritis (MGN) seems to be not infrequent in diabetics. We found it in renal biopsy specimens of 10 patients (from a total of 111 investigated by semithin technique). In all of those specimens which were also examined by immunofluorescence technique the diagnosis was confirmed (6 times out of 44 diabetics). All cases with MGN showed proteinuria, most of them a nephrotic syndrome. In 3 patients we observed a combination of MGN with diabetic glomerulosclerosis (GS). Conventional paraffin sections are inadequate for the diagnosis of MGN and the certain distinction from GS.

摘要

膜性肾小球肾炎(MGN)在糖尿病患者中似乎并不罕见。我们在10例患者的肾活检标本中发现了该病(在总共111例采用半薄切片技术检查的患者中)。在所有同时采用免疫荧光技术检查的标本中,诊断均得到证实(44例糖尿病患者中有6例)。所有MGN病例均有蛋白尿,其中大多数为肾病综合征。在3例患者中,我们观察到MGN与糖尿病肾小球硬化症(GS)并存。传统石蜡切片不足以诊断MGN以及将其与GS明确区分开来。

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