Sander P, Kelényi G
Zentralbl Allg Pathol. 1983;127(3-4):265-74.
On the basis of 8 biopsy and 3 autopsy cases of the Pathological Department, Schwerin County Hospital and of 4 selected biopsy and autopsy cases of the Department of Pathology, Medical University of Pécs, the pathomorphological diagnosis and differential diagnosis of angioimmunoblastic lymphadenopathy (AIBLP) or lymphogranulomatosis X are discussed. Borderline lesions between common reactive changes and AIBLP are high-grade paracortical hyperplasia and the so-called angioimmunoblastic reaction (AIBR) which may be associated with a partial transformation of lymph node structure. On the other hand, AIBLP should be differentiated from malignant lymphomas (immunoblastoma, T-zone lymphoma, Hodgkin's disease). The polyclonality of plasma cells, the presence of mature lymphocytes in higher numbers, the low mitotic rate, the absence of atypical giant cells all speak for AIBLP. AIBLP can be subdivided into several types (immunoblast-rich, plasma cell-rich, mixed cell type, epitheloid cell-rich type and lymphocyte-rich type. Lennert et al. 1979), the prognostic relevance of which should be assessed on a large number of cases.
基于什未林县医院病理科的8例活检和3例尸检病例以及佩奇医科大学病理科挑选的4例活检和尸检病例，对血管免疫母细胞性淋巴结病（AIBLP）或X线淋巴肉芽肿病的病理形态学诊断及鉴别诊断进行了讨论。常见反应性改变与AIBLP之间的临界病变为高度副皮质增生以及所谓的血管免疫母细胞反应（AIBR），后者可能伴有淋巴结结构的部分转化。另一方面，AIBLP应与恶性淋巴瘤（免疫母细胞瘤、T区淋巴瘤、霍奇金病）相鉴别。浆细胞的多克隆性、大量成熟淋巴细胞的存在、低有丝分裂率以及无非典型巨细胞均支持AIBLP的诊断。AIBLP可分为几种类型（富含免疫母细胞型、富含浆细胞型、混合细胞型、富含上皮样细胞型和富含淋巴细胞型。伦纳特等人，1979年），其预后相关性应通过大量病例进行评估。
