Edjtehadi M, Howard B R
Can J Comp Med. 1978 Jul;42(3):364-7.
Experiments have been carried out on 20 adult fat-tailed ewes to determine the effects of thiopental sodium, methoxyflurane and halothane on acid-base status of the saliva loss during prolonged surgical anaesthesia. The rate of loss of base in saliva depends on the volume of saliva produced, which fell sharply at the onset of anesthesia with the volatile anaesthesia. Plasma pH and plasma pvCO2 excess were both increased by the volatile anaesthetics but fell sharply during thiopental anaesthesia. Plasma pH and plasma PvCO2 showed no consistent relationship.
已对20只成年肥尾母羊进行实验,以确定硫喷妥钠、甲氧氟烷和氟烷对长时间手术麻醉期间唾液流失酸碱状态的影响。唾液中碱的流失速率取决于唾液分泌量,在挥发性麻醉开始时唾液分泌量急剧下降。挥发性麻醉剂可使血浆pH值和血浆过量二氧化碳分压升高,但在硫喷妥钠麻醉期间急剧下降。血浆pH值和血浆二氧化碳分压之间没有一致的关系。