Aznar Aznar A, López Alonso A, Moratinos Palomero P, Prieto Santos A, García de Viedma A L, Fernández Criado C, Domínguez Rojas V, Casimiro Sansegundo C
An Esp Pediatr. 1983 Mar;18(3):196-203.
A study was carried out on 40 dogs. Four groups of ten dogs each were established. A laparotomy group, a simple splenectomy group and two groups which underwent a selective autotransplant of the medium an deep layers of a centrifugated solution of splenic medulla respectively. Immunisation with BSA showed that humoral immune response with formation of anti-BSA antibodies is more intense in the control group which underwent laparotomy than in the splenectomised group. The response obtained in dogs subjected to autotransplant of deep layer is almost identical to that of the control group while that of the medium layer showed a slightly lower response. Cellular immune response is more accentuated in the group which underwent autotransplant from the deep layer, while those from the medium layer showed a higher response than that of the splenectomised group.
对40只狗进行了一项研究。将它们分成四组，每组十只。一组进行剖腹手术，一组进行单纯脾切除术，另外两组分别接受脾脏髓质离心溶液中层和深层的选择性自体移植。用牛血清白蛋白进行免疫后发现，进行剖腹手术的对照组中，形成抗牛血清白蛋白抗体的体液免疫反应比脾切除组更强烈。接受深层自体移植的狗所产生的反应与对照组几乎相同，而中层自体移植组的反应略低。深层自体移植组的细胞免疫反应更明显，而中层自体移植组的反应比脾切除组更高。
