Erkkola R, Kero P, Kanto J, Aaltonen L
Ann Clin Res. 1983 Apr;15(2):88-91.
A case of severe abuse of phenothiazines, benzodiazepines and barbiturates and smoking 40 cigarettes a day throughout pregnancy is described. Intoxication requiring hospitalization occurred 3 times during pregnancy. The mother was hospitalized for the last 10 days of pregnancy and only lorazepam and oxazepam were given in order to improve the co-operation of the mother and to alleviate fetal withdrawal symptoms. At 39 weeks a healthy baby boy of 3150 g was delivered. Obvious withdrawal symptoms in the neonate appeared at the age of 20 hours. Due to repeated drug intoxications of the mother after discharge, the baby was located in a custody home. At his postnatal examination at the age of 3 months the baby appeared somatically and neurologically unaffected. A slight muscular hypotonia of lower limbs was suspected, though. At check-ups at the age of 6 and 12 months the baby was normal in all respects.
本文描述了一例在整个孕期严重滥用吩噻嗪类、苯二氮䓬类和巴比妥类药物且每天吸烟40支的病例。孕期发生了3次需要住院治疗的中毒情况。母亲在怀孕的最后10天住院，仅给予劳拉西泮和奥沙西泮，以提高母亲的配合度并减轻胎儿戒断症状。孕39周时，产下一名体重3150克的健康男婴。新生儿在20小时时出现明显的戒断症状。由于母亲出院后反复药物中毒，婴儿被安置在托管之家。在3个月大的产后检查中，婴儿的身体和神经方面未见异常。不过，怀疑有轻微的下肢肌张力减退。在6个月和12个月的检查中，婴儿各方面均正常。
