Niimoto M, Matsuki K, Hirono M, Hattori T
Gan To Kagaku Ryoho. 1983 Feb;10(2 Pt):194-7.
During the period from June 1973 to August 1982, thirteen patients with gastric cancer and seven patients with colorectal cancer received surgical treatment due to the obstruction of the rectum or ureter. Of thirteen gastric cancer patients, 11 underwent the formation of the artificial anus for rectal obstruction. Nephrostomy was performed in 4 gastric cancer patients with ureteral obstruction. Seven patients with colorectal cancer underwent the formation of the artificial anus for rectal obstruction. In the recurrent cancer of the gastrointestinal tract, obstruction of the rectum or ureter mainly occurred due to peritoneal invasion or tumor formation. During laparotomy, OK-432, a Streptococcal preparation, was administered with a large dose of 100 K. E. to the patients with advanced or recurrent cancer foci. The prognosis for those patients was poor, and the main reason for poor survival was the advancement of disease in the cases of rectal or ureteral obstruction.
在1973年6月至1982年8月期间，13例胃癌患者和7例结直肠癌患者因直肠或输尿管梗阻接受了手术治疗。13例胃癌患者中，11例因直肠梗阻进行了人工肛门造瘘术。4例因输尿管梗阻的胃癌患者进行了肾造瘘术。7例结直肠癌患者因直肠梗阻进行了人工肛门造瘘术。在胃肠道复发癌中，直肠或输尿管梗阻主要是由于腹膜侵犯或肿瘤形成所致。在剖腹手术中，对有晚期或复发癌灶的患者大剂量（100K.E.）给予链球菌制剂OK-432。这些患者的预后较差，生存不佳的主要原因是直肠或输尿管梗阻病例中的疾病进展。
