一名患有45,X/46,X;mar嵌合体的女孩发生侵袭性无性细胞瘤。
Invasive dysgerminoma in a girl with 45,X/46,X; mar mosaicism.
作者信息
Pfeiffer R A, Tietze U, Krone H A, Schaaff A, Dhom G, Peter H
出版信息
Arch Gynecol. 1983;233(2):141-7. doi: 10.1007/BF02114790.
PMID:6882018
Abstract
We report a 16-year-old girl with features of Turner's syndrome from whom an invasive dysgerminoma was removed. Cytotoxic drugs were given for the next 12 months. Mosaicism of two karyotypes (45,X/46,X; mar) was found in various tissues. The literature is reviewed with special regard to cytogenetic findings and prognosis of malignant growth and differentiation of dysgenetic gonads.
摘要
我们报告了一名患有特纳综合征特征的16岁女孩，她接受了侵袭性无性细胞瘤切除术。在接下来的12个月里给予了细胞毒性药物治疗。在各种组织中发现了两种核型（45,X/46,X；mar）的嵌合体。本文特别针对细胞遗传学发现以及发育异常性腺恶性生长和分化的预后对文献进行了综述。
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