唾液酸在人类精子膜中的分布。

Distribution of sialic acid in human sperm membranes.

作者信息

Levinsky H, Singer R, Malik Z, Sagiv M, Cohen A M, Servadio C, Allalouf D

出版信息

Arch Androl. 1983 Jun;10(3):209-12. doi: 10.3109/01485018308987566.

PMID:6882086

Abstract

Sialic acid was estimated both chemically in populations of heads and tails of spermatozoa from normospermic human seminal fluid and by transmission electron microscopy, using a specific labeling technique. The results of both procedures show that sialic acid is located exclusively in the head plasma membrane and in the acrosomal membranes. It is suggested that localization of sialic acid close to that reported for neuraminidase in sperm might be of importance in the fertilization process.

摘要

利用一种特定的标记技术，通过化学方法对正常精子精液中精子头部和尾部群体中的唾液酸进行了估算，并借助透射电子显微镜进行了观察。两种方法的结果均显示，唾液酸仅位于头部质膜和顶体膜中。有人提出，精子中唾液酸的定位与报道的神经氨酸酶的定位相近，这在受精过程中可能具有重要意义。