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[风疹与先天性白内障]

[Rubella and congenital cataracts].

作者信息

Celers J, Aymard M, Feingold J, Godde-Jolly D

出版信息

Arch Fr Pediatr. 1983 May;40(5):391-5.

PMID:6882129
Abstract

Between April 3, 1977 and June 6, 1980, 97 children with congenital cataracts and 97 evenly matched control children were examined in order to clarify the biological criteria of congenital rubella and to estimate its importance in the etiology of congenital cataracts. Although the age limit had been fixed at 60 months, the 1978 rubella outbreak accelerated the immunization in young children and resulted in difficulties in interpreting some results. All children presenting with congenital cataracts associated with clinical symptoms of rubella embryopathy displayed anti-rubella antibodies including anti-rubella IgM up to the 13th month: they represent 16% of cases with congenital cataracts in this series. The rubella etiology could not be proven in children with clinically isolated congenital cataracts.

摘要

在1977年4月3日至1980年6月6日期间,对97名先天性白内障患儿和97名匹配良好的对照儿童进行了检查,以明确先天性风疹的生物学标准,并评估其在先天性白内障病因学中的重要性。尽管年龄限制设定为60个月,但1978年的风疹疫情加速了幼儿免疫接种,导致部分结果难以解释。所有表现出与风疹胚胎病临床症状相关的先天性白内障患儿,直至13个月时均显示出抗风疹抗体,包括抗风疹IgM:在本系列先天性白内障病例中占16%。临床孤立性先天性白内障患儿无法证实风疹病因。

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