Biagi P, Iommi E, Spacone A, Mellone G
Arch Sci Med (Torino). 1983 Apr-Jun;140(2):215-9.
A case of febrile hepatic granulomatosis was examined and the many aetiologies to be considered in the differential diagnosis of the condition evaluated. This is not a separate disease but a specific histological peculiarity of the liver. The case in question was diagnosed as hepatic granulomatosis originating in sarcoidosis. This diagnosis requires, it is though, the presence of characteristic granulomas in the liver biopsy sample but more important in the Kweim reaction or preferably in more specific tissue biopsies (spleen, lymph nodes, mesentery). In the present case the histologically revealed initial cirrhosis may be purely concomitant though certain authorities believe that sarcoidotic hepatic granulomas may develop into cirrhosis.
对一例发热性肝肉芽肿病进行了检查，并评估了该病症鉴别诊断中需考虑的多种病因。这并非一种独立的疾病，而是肝脏特定的组织学特征。所讨论的病例被诊断为源自结节病的肝肉芽肿病。然而，这一诊断需要在肝活检样本中存在特征性肉芽肿，但更重要的是在Kveim反应中，或者最好在更具特异性的组织活检（脾脏、淋巴结、肠系膜）中发现。在本病例中，组织学显示的初期肝硬化可能纯属伴随情况，不过某些权威人士认为结节病性肝肉芽肿可能发展为肝硬化。
