Ben Hanan Y, Landshman N, Avni I, Karsik A, Belkin M
Br J Ophthalmol. 1983 Sep;67(9):635-7. doi: 10.1136/bjo.67.9.635.
We produced alkali burns (1.5 N NaOH) in the right eyes of 63 mice. Three weeks later the left eye of each mouse was similarly burned. All eyes were followed up weekly for 4 weeks after the burn and were graded according to the severity of the lesion. The lesions developed much faster and were more severe in the left eyes. These results suggest that the body's immune mechanism participates in the pathogenesis of alkali corneal burns and adversely affects the development of this condition.
我们在63只小鼠的右眼制造了碱烧伤（1.5N氢氧化钠）。三周后，对每只小鼠的左眼进行同样的烧伤。在烧伤后的4周内，每周对所有眼睛进行随访，并根据损伤的严重程度进行分级。左眼的损伤发展得更快且更严重。这些结果表明，机体的免疫机制参与了碱烧伤角膜的发病过程，并对该病症的发展产生不利影响。
